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      <title type="html">Total Syntheses of Tricrilactones D and F, Crispatumine I and ...</title>
    
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      Total Syntheses of Tricrilactones D and F, Crispatumine I and 2,3-trans-Crispatumine I(Brimble,2026)&lt;br/&gt;&lt;br/&gt;An organic chemistry minilecture on the &amp;#39;Bioinspired Total Syntheses of Tricrilactones D and F, Crispatumine I, and 2,3-trans-Crispatumine I&amp;#39; by Tashia Siew, Liam R. Hunt, Gabriel Chun Yi Ng, David Rennison and Margaret A. Brimble*. It features a Transannular Cyclisation Cascade to rapidly and efficiently construct the polycyclic framework of several biologically interesting natural products.&lt;br/&gt;SUPPORT THE CHANNEL ON PATREON:&lt;br/&gt;&lt;a href=&#34;https://www.patreon.com/SimplifyingSynthesis&#34;&gt;https://www.patreon.com/SimplifyingSynthesis&lt;/a&gt;&lt;br/&gt;Socials:&lt;br/&gt;&lt;a href=&#34;https://www.instagram.com/simplifyingsynthesis/&#34;&gt;https://www.instagram.com/simplifyingsynthesis/&lt;/a&gt;&lt;br/&gt;&lt;a href=&#34;https://twitter.com/SimplifyingSyn1&#34;&gt;https://twitter.com/SimplifyingSyn1&lt;/a&gt;&lt;br/&gt;References:&lt;br/&gt;Angewandte Chemie 2023, 135, DOI 10.1002/ange.202300773 (Isolation)&lt;br/&gt;Bioorg. Chem. 2026, 175,109768 (Isolation)&lt;br/&gt;Org. Lett., 2017, 19, 24, 6502–6505 (IBX Mechanism)&lt;br/&gt;Angew. Chem. Int. Ed.2025, 64, DOI 10.1002/anie.202419989.(Cordycicadin synthesis)&lt;br/&gt;&lt;br/&gt;&lt;a href=&#34;https://www.youtube.com/watch?v=1_alLXUjbKA&#34;&gt;https://www.youtube.com/watch?v=1_alLXUjbKA&lt;/a&gt;&lt;br/&gt; &lt;img src=&#34;https://i2.ytimg.com/vi/1_alLXUjbKA/hqdefault.jpg&#34;&gt; &lt;br/&gt;&lt;br/&gt;#totalsyntheses #crispatumine #tricrilactones #bioinspiredtotal #davidrennison #gabrielchun #tashiasiew #isolation #angewandtechemie #cyclisationcascade&lt;br/&gt;&lt;br/&gt;#rss #feeds #linksharing #qwibbit
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    <updated>2026-11-01T07:35:25Z</updated>
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