Nostr notes by Peter Attia MD (RSS Feed)

#410 ‒ The biology of pregnancy: physiologic adaptation, ...

2026-10-05T04:15:00Z

#410 ‒ The biology of pregnancy: physiologic adaptation, gestational diabetes, preeclampsia, childbirth, and long-term maternal health | Kathryn Gray, M.D., Ph.D.

“[Pregnancy] It’s a cardiovascular stress test because the plasma volume expands so much. It is a metabolic stress test because there's increased insulin resistance.”‒ Katie Gray

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https://peterattiamd.com/kathryngray/

Myostatin inhibitors and the paradox of larger but weaker muscles ...

2026-10-03T11:00:00Z

Myostatin inhibitors and the paradox of larger but weaker muscles

Drugs, new and old, that preserve lean mass, but fail to boost strength

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https://peterattiamd.com/myostatin-inhibitors-and-larger-but-weaker-muscles/

The end of Alzheimer’s? A prevention strategy is in clinical ...

2026-09-30T06:00:00Z

The end of Alzheimer’s?

A prevention strategy is in clinical trials

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https://peterattiamd.com/end-of-alzheimers/

#409 ‒ Inside modern drug development: the science, economics, ...

2026-09-28T04:15:00Z

#409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles behind bringing new medicines to patients | Lloyd Klickstein, M.D., Ph.D.

“The way this works is… at a very high level, making a new drug that's used by many people takes longer, is more expensive, and takes as many people as building the biggest skyscraper in the world. Think the Burj Khalifa.”‒ Lloyd Klickstein

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https://peterattiamd.com/lloydklickstein2/

Prioritizing health interventions Separating high-impact ...

2026-09-26T11:00:00Z

Prioritizing health interventions

Separating high-impact interventions from those that matter only at the margins

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https://peterattiamd.com/prioritizing-interventions/

#408 ‒ AMA #89: Thyroid health: interpreting symptoms, ...

2026-09-21T04:15:00Z

#408 ‒ AMA #89: Thyroid health: interpreting symptoms, diagnosing and treating dysfunction, and navigating the gray zone

“The goal of this podcast, of course, is then to walk people through the physiology carefully enough that you can see both the grains of truth on each side of those schools of thought, but perhaps more importantly, what they might be missing and therefore where we can hopefully land on a place to treat people.”‒ Peter Attia

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https://peterattiamd.com/ama89/

Can semaglutide slow aging? A new study found that semaglutide ...

2026-09-19T11:00:00Z

Can semaglutide slow aging?

A new study found that semaglutide extended median lifespan and improved several measures of aging in female mice—but the headline requires careful interpretation.

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https://peterattiamd.com/can-semaglutide-slow-aging/

#407 ‒ Preventing cardiovascular and Alzheimer’s disease: ...

2026-09-14T04:15:00Z

#407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early, APOE4, and promising new therapies | Michael Davidson, M.D.

“I mean we have the knowledge to prevent heart disease now. It's applying it earlier in life that really makes the difference. That's my pitch to the 30-year-old, and there's a lot of pushback.”‒ Michael Davidson

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https://peterattiamd.com/michaeldavidson/

Nearsightedness is rising. Are screens to blame? How screens, ...

2026-09-12T11:00:00Z

Nearsightedness is rising. Are screens to blame?

How screens, outdoor light, and near work may influence myopia

The post https://peterattiamd.com/nearsightednessandscreens/ appeared first on https://peterattiamd.com.

https://peterattiamd.com/nearsightednessandscreens/

Vaginal estrogen: a potentially life-saving therapy Local ...

2026-09-05T11:00:00Z

Vaginal estrogen: a potentially life-saving therapy

Local estrogen therapy treats symptoms, prevents UTIs, is safe, and likely saves lives

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https://peterattiamd.com/vaginal-estrogen/

#406 ‒ Migraine, cluster headache, and tension headache: ...

2026-08-31T04:15:00Z

#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D.

“People should have hope, in the sense that it's very important to be as empowered as possible by keeping a log of information, by providing their clinicians or the treating physicians or providers with the details of their headache, and recognizing the importance of those lifestyle factors, which can't be overstated.”‒ Brian Grosberg

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https://peterattiamd.com/briangrosberg/

A better way to think about Zone 2 The balancing act of volume ...

2026-08-29T11:00:00Z

A better way to think about Zone 2

The balancing act of volume and fatigue

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https://peterattiamd.com/a-better-way-to-think-about-zone-2/

GLP-1 medications beyond weight loss: how far could their ...

2026-08-27T04:00:00Z

GLP-1 medications beyond weight loss: how far could their benefits extend?

What the evidence says about their growing list of established and emerging uses

The post https://peterattiamd.com/glp-1-medications-beyond-weight-loss/ appeared first on https://peterattiamd.com.

https://peterattiamd.com/glp-1-medications-beyond-weight-loss/

#405 ‒ AMA #88: Metabolic liver health: how to assess risk, ...

2026-08-24T04:15:00Z

#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease

“The disease can be reversible and that's why we make so much hay about intervening early. We address the metabolic drivers, and we see that steatosis and fibrosis in the earlier stages can regress, especially the earlier the fibrosis is caught.”‒ Peter Attia

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https://peterattiamd.com/ama88/

Gum recession: a common oral health issue that often goes ...

2026-08-22T11:00:00Z

Gum recession: a common oral health issue that often goes unnoticed

Gum recession is common, often silent, and sometimes worsened by the very habits meant to protect your teeth.

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https://peterattiamd.com/gum-recession/

#404 ‒ Mental health beyond neurotransmitters: the role of ...

2026-08-17T04:15:00Z

#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn’t enough, and the future of psychedelic therapies | Linus Abrams, M.D.

“What I finally decided was the organizing principle was that psychiatry aims at reduction of symptoms, but not restoration of the full human experience that makes life most worthwhile.”‒ Linus Abrams

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https://peterattiamd.com/linusabrams/

Multifactorial trials: taking apart the kitchen sink What a ...

2026-08-15T11:00:00Z

Multifactorial trials: taking apart the kitchen sink

What a multifactorial trial can prove, what it can't, and why the difference matters more than it seems

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https://peterattiamd.com/multifactorial-trials/

#403 ‒ Peptides: separating scientific promise from marketing ...

2026-08-10T04:15:00Z

#403 ‒ Peptides: separating scientific promise from marketing hype

“Peptides as a class can be genuinely powerful, which is a reason to be more careful with them, not less. We can't normalize treating real drugs carelessly.” —Peter Attia

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https://peterattiamd.com/peptides/

Does protein restriction still make sense in modern kidney care? ...

2026-08-08T11:00:00Z

Does protein restriction still make sense in modern kidney care?

The case for limiting protein to protect the kidneys was built in a different era of nephrology.

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https://peterattiamd.com/protein-and-renal-function/

#402 ‒ NMR blood analysis: how heart disease risk, insulin ...

2026-08-03T04:15:00Z

#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.

“What is true is that NMR—a single scan—can tell you a heck of a lot more than just your cardiovascular risk, your inflammation level, your diabetes risk, your mortality risk.” —Jim Otvos

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https://peterattiamd.com/jimotvos/

Zero coronary calcium does not mean zero cardiovascular risk A ...

2026-08-01T11:00:00Z

Zero coronary calcium does not mean zero cardiovascular risk

A zero calcium score is useful, but it should not be used to dismiss sustained LDL-C elevation in young adults.

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https://peterattiamd.com/why-zero-coronary-calcium-does-not-mean-zero-risk/

#401 ‒ How curiosity transforms medicine: extraordinary ...

2026-07-27T04:15:00Z

#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare

“The history of medicine is full of examples where we didn't invent the underlying mechanism. We discovered it, understood it, and then engineered it into something useful.” —Peter Attia

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https://peterattiamd.com/medicalbreakthroughs/

Lithium and Alzheimer’s disease: what to weave of this LATTICE? ...

2026-07-25T11:00:00Z

Lithium and Alzheimer’s disease: what to weave of this LATTICE?

A negative clinical trial leaves open questions about lithium and Alzheimer’s disease.

The post https://peterattiamd.com/lithium-and-alzheimers-disease/ appeared first on https://peterattiamd.com.

https://peterattiamd.com/lithium-and-alzheimers-disease/

Organic food and your health: what are the stakes? From ...

2026-07-23T01:00:00Z

Organic food and your health: what are the stakes?

From pesticides and GMOs to nutrient content and antibiotic exposure, we investigate the case for eating organic food.

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https://peterattiamd.com/organic-food-and-your-health/

#400 ‒ AMA #87: Environmental pollution and longevity: air ...

2026-07-20T04:15:00Z

#400 ‒ AMA #87: Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks

"These are the tools to give you the 80/20 approach to engineer a reasonably safe environment from a pollution standpoint, without becoming a lifestyle devoid of any sanity.” —Peter Attia

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https://peterattiamd.com/ama87/

Does heat training build a better engine? Cautious optimism for ...

2026-07-18T11:00:00Z

Does heat training build a better engine?

Cautious optimism for the summer heat

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https://peterattiamd.com/does-heat-training-build-a-better-engine/

#399 ‒ The evolution of Alzheimer’s disease and dementia ...

2026-07-13T04:15:00Z

#399 ‒ The evolution of Alzheimer’s disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.

"Early diagnosis really does make a difference now in terms of changing the trajectory of someone's cognitive health.” —Gayatri Devi

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https://peterattiamd.com/gayatridevi/

Does losing sleep mean losing lifespan? What a new meta-analysis ...

2026-07-11T11:00:00Z

Does losing sleep mean losing lifespan?

What a new meta-analysis can’t tell us—and what we should do anyways

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https://peterattiamd.com/does-losing-sleep-mean-losing-lifespan/

Building strength and muscle mass: how to optimize training, ...

2026-07-06T04:15:00Z

Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)

“The more you move, the more you’re alive. The less you move, the less you’re alive.” —Peter Attia

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https://peterattiamd.com/strengthandmuscle/

#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better ...

2026-06-29T04:15:00Z

#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

“When patients are counseled thoroughly on how to consume protein [in the right amount] and how to properly engage in resistance training, we're seeing very little lean mass lost.” —Peter Attia

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https://peterattiamd.com/mp-files/ama-86-full-audio.mp3/

https://peterattiamd.com/ama86/

Lung cancer screening in never-smokers: the data Although not ...

2026-06-25T04:15:00Z

Lung cancer screening in never-smokers: the data

Although not endorsed by guidelines, evidence supports it as a rational choice

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https://peterattiamd.com/lung-cancer-screening-in-never-smokers/

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, ...

2026-06-22T04:15:00Z

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.

“If we diagnose an adolescent—or even young women—earlier, we can avoid 40% of the lesions or the disease burden.” —Renato Tomioka

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https://peterattiamd.com/renatotomioka/

#396 ‒ Breast cancer screening: understanding risk, deciding ...

2026-06-15T04:15:00Z

#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy

“The science here is not the bottleneck. The tools exist. The evidence is strong. What is missing is the bridge between what we know and what women are actually doing.” —Peter Attia

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https://peterattiamd.com/breastcancerscreening/

#395 – Brain lipidology: understanding APOE, cholesterol ...

2026-06-08T04:15:00Z

#395 – Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer’s disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.

"Unfortunately, a prevalent belief out there in the real world is ‘I don't ever want to lower LDL cholesterol too much, because I'll deprive the brain and I'll injure the brain’ . . .and that is not true." —Tom Dayspring

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https://peterattiamd.com/tomdayspring8/

#394 ‒ Sleep pharmacology: the role of medications in healthy ...

2026-06-01T04:15:00Z

#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements

“Different drugs vary in how quickly they work, how long they last, and which sleep problems they target. We need to match the medication's pharmacology to the patient's specific sleep challenges.” —Peter Attia

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https://peterattiamd.com/sleeppharmacology/

#393 ‒ AMA #85: A guide to medications and supplements: ...

2026-05-25T04:15:00Z

#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they’re working for you

“Poor problem definition almost guarantees some sort of false positive.” —Peter Attia

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https://peterattiamd.com/mp-files/ama-85-full-audio.mp3/

https://peterattiamd.com/ama85/

#392 – Genetic testing: when it’s valuable, how to choose the ...

2026-05-18T04:15:00Z

#392 – Genetic testing: when it’s valuable, how to choose the right test, and what to do with the results

“Like every tool we have in medicine, [genetic testing] has real strengths and real limitations, and its value depends almost entirely on how thoughtfully it is used.” —Peter Attia

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https://peterattiamd.com/genetictesting/

#391 ‒ Colorectal cancer screening: importance of early ...

2026-05-11T04:15:00Z

#391 ‒ Colorectal cancer screening: importance of early screening, colonoscopy as a screening and preventive tool, and how to build a personalized strategy

“Most cancers are something that happen to you, but colorectal cancer is one of the few that you can intercept before it even exists.” —Peter Attia

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https://peterattiamd.com/mp-files/colorectal-cancer-screening-full-audio.mp3/

https://peterattiamd.com/colorectalcancerscreening/

#390 ‒ AMA #84: Family health history, preventing heart ...

2026-05-04T04:15:00Z

#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration

“There's a risk to doing anything, and then there's a risk to NOT doing something.” —Peter Attia

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https://peterattiamd.com/mp-files/390-ama-84-full-audio.mp3/

https://peterattiamd.com/ama84/

#389 – Thinking scientifically: why it’s hard, why it ...

2026-04-27T04:15:00Z

#389 – Thinking scientifically: why it’s hard, why it matters, and a practical toolkit

“The goal of thinking scientifically is not simply to be right. It's to be less wrong over time. Science is a process built around that principle.” —Peter Attia

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https://peterattiamd.com/thinkingscientifically/

#388 — Prostate cancer screening: why current PSA guidelines ...

2026-04-20T04:15:00Z

#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives

“The timing of when you find the cancer is not a minor detail, it's arguably the determining factor in life and death.” —Peter Attia

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https://peterattiamd.com/prostatecancerscreening/

#387 – AMA #83: Peptides—evaluating the science, safety, and ...

2026-04-13T04:15:00Z

#387 – AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field

“The big picture is that peptides are a legitimate, powerful class of therapeutics, but the legitimacy is confined to a relatively narrow subset of them.” —Peter Attia

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https://peterattiamd.com/ama83/

#386 – Aging clocks—what they measure, how they work, and ...

2026-04-06T04:15:00Z

#386 – Aging clocks—what they measure, how they work, and their clinical and real-world relevance

"The biomarkers that capture aspects of the aging process could help us prioritize which ideas are worth testing more rigorously and putting more resources into.” —Peter Attia

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https://peterattiamd.com/agingclocks/

Thinking in trade-offs: a necessary antidote to diet tribalism ...

2026-03-30T18:00:00Z

Thinking in trade-offs: a necessary antidote to diet tribalism

Finding a diet that sustainably works for you is enough of a win. Why pretend it has no downsides?

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https://peterattiamd.com/mp-files/thinking-in-trade-offs-a-necessary-antidote-to-diet-tribalism.mp3/

https://peterattiamd.com/a-necessary-antidote-to-diet-tribalism/

#385 – AMA #82: Applying the tools of longevity in the real ...

2026-03-23T04:15:00Z

#385 – AMA #82: Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

“Everything we're doing is simultaneously geared towards reducing the risk of chronic disease but also improving healthspan." —Peter Attia

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https://traffic.libsyn.com/secure/peterattiadrive/EP.XX_-_Rapid_Fire_AMA_82_PRIVATE.mp3

https://peterattiamd.com/ama82/

#384 – Special episode — Obicetrapib: The CETP inhibitor with ...

2026-03-16T04:15:00Z

#384 – Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer’s prevention

"It's hard for me to mask my personal optimism around this. I love the biological plausibility of this, and I think that obicetrapib has done something that it's four predecessors has failed to do." —Peter Attia

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https://peterattiamd.com/obicetrapib/

#383 ‒ AMA #81: Biological aging tests, longevity training, ...

2026-03-09T04:15:00Z

#383 ‒ AMA #81: Biological aging tests, longevity training, emerging therapies, GLP-1 RAs, sun exposure, and more

"If there was anything wrong with seed oils in modest quantities (again beyond the caloric effects of any oil), I'm still waiting for someone to present a convincing case for that.” —Peter Attia
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https://traffic.libsyn.com/secure/peterattiadrive/The_Drive_-_AMA_81_-_PRIVATE_V4.mp3

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A failed endpoint is not a failed technology GRAIL’s landmark ...

2026-03-07T12:00:00Z

A failed endpoint is not a failed technology

GRAIL’s landmark cancer screening trial missed its composite endpoint, but a closer look at what was reported—and what wasn’t—suggests the verdict is far from settled.
The post https://peterattiamd.com/grail-cancer-screening-trial/
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https://peterattiamd.com/grail-cancer-screening-trial/

#382 ‒ AMA #80: Longevity optimization through strength ...

2026-03-02T05:15:00Z

#382 ‒ AMA #80: Longevity optimization through strength benchmarks, VO₂ max targets, nutrition principles, brain health, supplements, GLP-1 RAs, wearables, and more

"There doesn't appear to be an intervention that is more protective of the brain than exercise.” —Peter Attia
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https://traffic.libsyn.com/secure/peterattiadrive/The_Drive_-_Special_AMA_-_PRIVATE.mp3

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Does lowering cholesterol harm the brain? A large genetic study ...

2026-02-28T12:00:00Z

Does lowering cholesterol harm the brain?

A large genetic study suggests lifelong reductions in atherogenic lipoproteins are associated with lower—not higher—dementia risk.
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https://peterattiamd.com/does-lowering-cholesterol-harm-the-brain/

GLP-1 drugs fail to slow cognitive decline in Alzheimer’s ...

2026-02-21T12:00:00Z

GLP-1 drugs fail to slow cognitive decline in Alzheimer’s disease

A disappointing result, but there’s still hope for prevention
The post https://peterattiamd.com/glp-1-drugs-and-alzheimers-disease/
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https://peterattiamd.com/glp-1-drugs-and-alzheimers-disease/

Metformin misses the mark? A closer look at the MET-PREVENT trial ...

2026-01-31T12:00:00Z

Metformin misses the mark?

A closer look at the MET-PREVENT trial and what its null results reveal about aging interventions and trial design
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https://peterattiamd.com/does-metformin-miss-the-mark/

#381 ‒ Alzheimer’s disease in women: how hormonal transitions ...

2026-01-26T05:15:00Z

#381 ‒ Alzheimer’s disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.

“What we and others have shown is that Alzheimer's is not a disease of old age. It's a disease of midlife with symptoms that start in old age.” —Lisa Mosconi
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https://peterattiamd.com/lisamosconi/

The absence of atherosclerosis is not an excuse to ignore heart ...

2026-01-24T12:00:00Z

The absence of atherosclerosis is not an excuse to ignore heart attack symptoms—especially for women

Atherosclerosis is not the only possible cause of a heart attack (myocardial infarction), and women are more prone to alternative causes than men
The post https://peterattiamd.com/non-atherosclerotic-heart-attacks/
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https://peterattiamd.com/non-atherosclerotic-heart-attacks/

#380 ‒ The seed oil debate: are they uniquely harmful relative ...

2026-01-19T05:15:00Z

#380 ‒ The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D.

“The scientific method is perfect. It is a perfect method, but it is done by people who are not.” —Layne Norton
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https://peterattiamd.com/laynenorton4/

A recent study on exercise intensity has been widely ...

2026-01-17T12:00:00Z

A recent study on exercise intensity has been widely misinterpreted

A viral wearable-data study suggests that one minute of vigorous exercise can replace 156 minutes of low-intensity movement. A closer look at the data tells a different story.
The post https://peterattiamd.com/exercise-intensity-equivalence/
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https://peterattiamd.com/exercise-intensity-equivalence/

#379 – AMA #79: A guide to cardiorespiratory training at any ...

2026-01-12T05:15:00Z

#379 – AMA #79: A guide to cardiorespiratory training at any fitness level to improve healthspan, lifespan, and long-term independence

“Our objective is to be able to maintain optionality around being physical for as long as possible, and that is tantamount to having as high a VO2 max as possible, in addition to being as strong as possible.” —Peter Attia
The post https://peterattiamd.com/ama79/
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https://traffic.libsyn.com/secure/peterattiadrive/EP.379_-_AMA_79_-_PRIVATE.mp3

https://peterattiamd.com/ama79/

Pitting facts against sensationalism regarding the role of LDL ...

2026-01-10T12:00:00Z

Pitting facts against sensationalism regarding the role of LDL cholesterol in ASCVD

Social media personalities have been challenging conventional wisdom on atherosclerosis, but their evidence doesn’t hold up to scrutiny
The post https://peterattiamd.com/the-role-of-ldl-cholesterol-in-ascvd/
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https://peterattiamd.com/the-role-of-ldl-cholesterol-in-ascvd/

#378 ‒ Women’s health and performance: how training, ...

2026-01-05T05:15:00Z

#378 ‒ Women’s health and performance: how training, nutrition, and hormones interact across life stages | Abbie Smith-Ryan, Ph.D.

“We really need to take advantage of lifestyle behavior changes [during that perimenopause window] to have this lifelong impact to improve health span.” —Abbie Smith-Ryan
The post https://peterattiamd.com/abbiesmithryan/
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https://peterattiamd.com/abbiesmithryan/

Oldies-But-Goodies: January 2026 Edition Highlighting past ...

2026-01-03T12:00:00Z

Oldies-But-Goodies: January 2026 Edition

Highlighting past articles on two common target areas for new year’s resolutions: nutrition and exercise
The post https://peterattiamd.com/oldies-but-goodies-january-2026/
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https://peterattiamd.com/oldies-but-goodies-january-2026/

Using “atomic habits” to reach your health goals A special ...

2025-12-27T12:00:00Z

Using “atomic habits” to reach your health goals

A special end-of-year newsletter on how you can apply James Clear’s laws of behavior change to a few of the actionable steps we learned about on The Drive in 2025
The post https://peterattiamd.com/using-atomic-habits-to-reach-your-health-goals/
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https://peterattiamd.com/using-atomic-habits-to-reach-your-health-goals/

#377 ‒ Special episode: Understanding true happiness and the ...

2025-12-22T05:15:00Z

#377 ‒ Special episode: Understanding true happiness and the tools to cultivate a meaningful life—insights from past interviews with Arthur Brooks

“The money, power, pleasure, and fame that are supposed to bring you undying happiness are false promises.” —Arthur Brooks
The post https://peterattiamd.com/bestofbrooks/
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https://peterattiamd.com/bestofbrooks/

There’s no age limit to living a full and happy life A ...

2025-12-20T12:00:00Z

There’s no age limit to living a full and happy life

A spotlight on a few inspirational people doing amazing things in their 90s and beyond
The post https://peterattiamd.com/marginal-decade-highlights/
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https://peterattiamd.com/marginal-decade-highlights/

#376 – AMA #78: Longevity interventions, exercise, diagnostic ...

2025-12-15T05:15:00Z

#376 – AMA #78: Longevity interventions, exercise, diagnostic screening, and managing high apoB, hypertension, metabolic health, and more

"I think all of us would love to live longer provided we can live better. And the good news is most of the things that you do to pursue healthspan will also improve lifespan." —Peter Attia
The post https://peterattiamd.com/ama78/
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https://traffic.libsyn.com/secure/peterattiadrive/EP.376_-_AMA_78_-_PRIVATE1.mp3

https://peterattiamd.com/ama78/

Hope for millions: the selfless work of the “world’s most ...

2025-12-13T12:00:00Z

Hope for millions: the selfless work of the “world’s most important doctor”

How Dr. Tom Catena has saved countless lives as the sole surgeon in the war-torn Nuba region of Sudan—and how you can help
The post https://peterattiamd.com/tom-catena-highlight/
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https://peterattiamd.com/tom-catena-highlight/

#375 – The ketogenic diet, ketosis, and hyperbaric oxygen: ...

2025-12-08T05:15:00Z

#375 – The ketogenic diet, ketosis, and hyperbaric oxygen: metabolic therapies for weight loss, cognitive enhancement, cancer, Alzheimer’s disease, brain injuries, and more | Dominic D’Agostino, Ph.D.

“If you elevate β-hydroxybutyrate in the blood 1 mM, that represents a 10% increase of available energy to the brain.” —Dom D’Agostino
The post https://peterattiamd.com/domdagostino2/
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https://peterattiamd.com/domdagostino2/

Is there a tradeoff between muscle strength and aerobic capacity? ...

2025-12-06T12:00:00Z

Is there a tradeoff between muscle strength and aerobic capacity?

A recent paper explores the limits between muscle fiber size and aerobic capacity. What does it mean for achieving your training goals?
The post https://peterattiamd.com/muscle-strength-and-aerobic-capacity/
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https://peterattiamd.com/muscle-strength-and-aerobic-capacity/

Alcohol and healthspan: knowing the risks and how to mitigate ...

2025-12-02T12:00:00Z

Alcohol and healthspan: knowing the risks and how to mitigate them

Alcohol consumption increases odds of developing chronic disease, but some individuals and situations carry more risk than others
The post https://peterattiamd.com/alcohol-and-healthspan/
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https://peterattiamd.com/alcohol-and-healthspan/

#374 – The evolutionary biology of testosterone: how it shapes ...

2025-12-01T05:15:00Z

#374 – The evolutionary biology of testosterone: how it shapes male development and sex-based behavioral differences | Carole Hooven, Ph.D.

“If we want to interfere with the male desire to compete, we are also interfering with whatever products we get or advances we get from that intense drive.” —Carole Hooven
The post https://peterattiamd.com/carolehooven/
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https://peterattiamd.com/carolehooven/

Oldies-But-Goodies: November 2025 Edition Highlighting past ...

2025-11-29T12:00:00Z

Oldies-But-Goodies: November 2025 Edition

Highlighting past articles on alcohol and cardiovascular health, aging bursts, exercise duration, hormone therapy, and the “cholesterol paradox”
The post https://peterattiamd.com/oldies-but-goodies-november-2025/
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https://peterattiamd.com/oldies-but-goodies-november-2025/

Cardiovascular benefits of GLP-1 drugs independent of weight loss ...

2025-11-22T12:00:00Z

Cardiovascular benefits of GLP-1 drugs independent of weight loss

Revising our earlier interpretation of SELECT trial data in light of new analyses
The post https://peterattiamd.com/cardiovascular-benefits-of-glp-1-drugs/
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https://peterattiamd.com/cardiovascular-benefits-of-glp-1-drugs/

#373 – Thyroid function and hypothyroidism: why current ...

2025-11-17T05:15:00Z

#373 – Thyroid function and hypothyroidism: why current diagnosis and treatment fall short for many, and how new approaches are transforming care | Antonio Bianco, M.D., Ph.D.

“Hypothyroidism is not that naive disease that we thought it was. It's a deadly disease. It can affect significantly the quality of life of patients." —Antonio Bianco
The post https://peterattiamd.com/antoniobianco/
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https://peterattiamd.com/antoniobianco/

Warning label requirements on hormone replacement products are ...

2025-11-15T12:00:00Z

Warning label requirements on hormone replacement products are soon to be lifted

The FDA has announced it will remove health warnings on HRT products, following the recommendations of an expert panel
The post https://peterattiamd.com/hrt-warning-label-requirements-to-be-lifted/
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https://peterattiamd.com/hrt-warning-label-requirements-to-be-lifted/

#372 – AMA #77: Dietary fiber and health outcomes: real ...

2025-11-10T05:15:00Z

#372 – AMA #77: Dietary fiber and health outcomes: real benefits, overhyped claims, and practical applications

“Combining viscous, quickly fermented, slowly fermented, and insoluble fibers will give you the broadest spectrum of benefit—supporting metabolic health, stool regularity, and feeding your gut biome in the best way possible.” —Peter Attia
The post https://peterattiamd.com/ama77/
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https://traffic.libsyn.com/secure/peterattiadrive/EP.372_-_AMA_77_-_PRIVATE.mp3

https://peterattiamd.com/ama77/

Focusing on what really matters for reducing your risk of death ...

2025-11-08T12:00:00Z

Focusing on what really matters for reducing your risk of death

Building on recent analysis of U.S. media coverage and mortality, we assessed how our own focus aligns with real health risks.
The post https://peterattiamd.com/what-really-matters-for-reducing-your-risk-of-death/
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https://peterattiamd.com/what-really-matters-for-reducing-your-risk-of-death/

#371 ‒ Women’s sexual health: understanding desire, arousal, ...

2025-11-03T05:15:00Z

#371 ‒ Women’s sexual health: understanding desire, arousal, and orgasms, navigating perimenopause with contraceptives and hormone therapy, enhancing sexual comfort and satisfaction, and more | Sally Greenwald, M.D., M.P.H.

"I'm most excited about the new information that we have coming in about hormone options in terms of how we provide menopause hormone therapy and how we treat perimenopause." —Sally Greenwald
The post https://peterattiamd.com/sallygreenwald/
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https://peterattiamd.com/sallygreenwald/

Does eating more protein burn more calories? Metabolizing dietary ...

2025-11-01T11:00:00Z

Does eating more protein burn more calories?

Metabolizing dietary protein requires more energy than metabolizing other macronutrients, but is the effect large enough to matter?
The post https://peterattiamd.com/does-eating-more-protein-burn-more-calories/
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https://peterattiamd.com/does-eating-more-protein-burn-more-calories/

#370 – AMA #76: Peter evaluates longevity drugs, aspirin for ...

2025-10-27T04:15:00Z

#370 – AMA #76: Peter evaluates longevity drugs, aspirin for CVD, and strategies to improve muscle mass — promising, proven, fuzzy, noise, or nonsense?

"Protein intake stimulates muscle protein synthesis, MPS, which is the necessary tool to fuel muscle growth in response to the adaptations of muscles under resistance training." — Peter Attia
The post https://peterattiamd.com/ama76/
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https://traffic.libsyn.com/secure/peterattiadrive/EP.370_-_AMA_76_-_PRIVATE.mp3

https://peterattiamd.com/ama76/

A critical look at the lifespan-extending promise of psilocybin ...

2025-10-25T11:00:00Z

A critical look at the lifespan-extending promise of psilocybin

Early results hint at lifespan extension with psilocybin, but is this science ready to inform human aging?
The post https://peterattiamd.com/psilocybin-and-lifespan/
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https://peterattiamd.com/psilocybin-and-lifespan/

Research Worth Sharing: October 2025 Edition Creatine and ...

2025-10-18T11:00:00Z

Research Worth Sharing: October 2025 Edition

Creatine and cognition, anti-inflammatory effects of probiotics, frailty and hospital outcomes, metformin for longevity, and lipid-lowering drugs
The post https://peterattiamd.com/research-worth-sharing-october-2025/
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https://peterattiamd.com/research-worth-sharing-october-2025/

#368 ‒ The protein debate: optimal intake, limitations of the ...

2025-10-13T04:15:00Z

#368 ‒ The protein debate: optimal intake, limitations of the RDA, whether high-protein intake is harmful, and how to think about processed foods | David Allison, Ph.D.

“It's one thing after another where people look for the villains and the heroes and the angels and the demons in food.” —David Allison
The post https://peterattiamd.com/davidallison3/
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https://peterattiamd.com/davidallison3/

Artificially sweetened beverages for metabolic health: motivation ...

2025-10-11T11:00:00Z

Artificially sweetened beverages for metabolic health: motivation matters

For body weight, why you switch from sugar-sweetened beverages to “diet” options may be even more important than whether you switch
The post https://peterattiamd.com/artificially-sweetened-beverages-for-metabolic-health/
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https://peterattiamd.com/artificially-sweetened-beverages-for-metabolic-health/

#367 – Tylenol, pregnancy, and autism: What recent studies show ...

2025-10-06T04:15:00Z

#367 – Tylenol, pregnancy, and autism: What recent studies show and how to interpret the data

“Science is not about being right or wrong in an absolute sense. It's really about constantly updating our priors, understanding the probability of something as new evidence becomes emergent.” —Peter Attia
The post https://peterattiamd.com/tylenolandautism/
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https://peterattiamd.com/tylenolandautism/

When zero doesn’t mean zero: the limits of coronary calcium in ...

2025-10-04T11:00:00Z

When zero doesn’t mean zero: the limits of coronary calcium in women

Coronary artery calcium scoring has revolutionized cardiovascular prevention. But in women, it sometimes underestimates the risk.
The post https://peterattiamd.com/cac-in-women/
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https://peterattiamd.com/cac-in-women/

#366 ‒ Transforming education with AI and an individualized, ...

2025-09-29T04:15:00Z

#366 ‒ Transforming education with AI and an individualized, mastery-based education model | Joe Liemandt

“When you use these learning science-based AI tutors and the apps that we have, kids can learn 10 times faster.” —Joe Liemandt
The post https://peterattiamd.com/joeliemandt/
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https://peterattiamd.com/joeliemandt/

Announcing a special episode on autism and acetaminophen We’re ...

2025-09-27T11:00:00Z

Announcing a special episode on autism and acetaminophen

We’re preparing a detailed discussion of the claims and evidence regarding potential links between prenatal acetaminophen exposure and autism risk
The post https://peterattiamd.com/autism-and-acetaminophen-episode-announcement/
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https://peterattiamd.com/autism-and-acetaminophen-episode-announcement/

365 ‒ Training for longevity: A roundtable on building ...

2025-09-22T04:15:00Z

365 ‒ Training for longevity: A roundtable on building strength, preventing injury, meeting protein needs, guidance for women and youth athletes, and more | Gabrielle Lyon, Mike Boyle, Jeff Cavaliere

“There's nothing more important for maintaining health and wellness than taking care of muscle health.”‒ Gabrielle Lyon
The post https://peterattiamd.com/trainingforlongevity/
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https://peterattiamd.com/trainingforlongevity/

Cautious optimism over lithium orotate as a treatment for ...

2025-09-20T11:00:00Z

Cautious optimism over lithium orotate as a treatment for Alzheimer’s disease

A recent study in mice offers hope for greater efficacy concerning a treatment that has already captured researchers’ attention
The post https://peterattiamd.com/lithium-and-alzheimers/
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https://peterattiamd.com/lithium-and-alzheimers/

#364 – AMA #75: Diets: how to evaluate and implement any diet ...

2025-09-15T04:15:00Z

#364 – AMA #75: Diets: how to evaluate and implement any diet including keto, carnivore, vegan, Mediterranean, and more

"The best diet is the one that simultaneously meets the core physiologic needs, the five legs of the table, and also addresses your own individual goals and preferences." —Peter Attia
The post https://peterattiamd.com/ama75/
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https://traffic.libsyn.com/secure/peterattiadrive/The_Drive_-_AMA_75_PRIVATE_V2.mp3

https://peterattiamd.com/ama75/

Preventing seasonal declines in vitamin D with exercise A recent ...

2025-09-13T11:00:00Z

Preventing seasonal declines in vitamin D with exercise

A recent study shows that moderate-intensity exercise can offset the drop in vitamin D that many experience during winter months
The post https://peterattiamd.com/vitamin-d-and-exercise/
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https://peterattiamd.com/vitamin-d-and-exercise/

#363 ‒ A new frontier in neurosurgery: restoring brain function ...

2025-09-08T04:15:00Z

#363 ‒ A new frontier in neurosurgery: restoring brain function with brain-computer interfaces, advancing glioblastoma care, and new hope for devastating brain diseases | Edward Chang, M.D.

“It's a super exciting time because every time we unlock essentially a function of a certain part of the brain, there's a very high probability that there's going to be a therapy either through a brain-computer interface or through a new biological approach.” —Edward Chang
The post https://peterattiamd.com/edwardchang/
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https://peterattiamd.com/edwardchang/

Can extreme calorie restriction enhance human lifespan? A study ...

2025-09-06T11:00:00Z

Can extreme calorie restriction enhance human lifespan?

A study in mice demonstrated impressive lifespan extension with extreme calorie restriction, but will results translate outside a research setting?
The post https://peterattiamd.com/calorie-restriction-and-lifespan/
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https://peterattiamd.com/calorie-restriction-and-lifespan/

Oldies-But-Goodies, August 2025 Edition Highlighting past ...

2025-08-30T11:00:00Z

Oldies-But-Goodies, August 2025 Edition

Highlighting past newsletters on melatonin supplements, hearing and dementia, AI in health assessments, vegan diets, and metabolic health
The post https://peterattiamd.com/oldies-but-goodies-august-2025/
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https://peterattiamd.com/oldies-but-goodies-august-2025/

#362 ‒ Understanding anxiety: defining, assessing, and treating ...

2025-08-25T04:15:00Z

#362 ‒ Understanding anxiety: defining, assessing, and treating health anxiety, OCD, and the spectrum of anxiety disorders | Josh Spitalnick, Ph.D., A.B.P.P.

"Avoidance is a behavioral coping tool that's highly effective in the moment for the anxiety, but ineffective long-term for functioning, that is shared amongst almost all the anxiety disorders.” —Josh Spitalnick
The post https://peterattiamd.com/joshspitalnick/
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https://peterattiamd.com/joshspitalnick/

#361 – AMA #74: Sugar and sugar substitutes: weight control, ...

2025-08-18T04:15:00Z

#361 – AMA #74: Sugar and sugar substitutes: weight control, metabolic effects, and health trade-offs

“When you live in a black and white world, and everything has to be good or bad, and natural is good and not natural is bad, and you are a robot, life is a painful place to exist.” —Peter Attia
The post https://peterattiamd.com/ama74/
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https://traffic.libsyn.com/secure/peterattiadrive/EP.361_-_AMA_74_PRIVATE_V2.mp3

https://peterattiamd.com/ama74/

Weighted vests for weight-loss maintenance? A new study tested ...

2025-08-16T11:00:00Z

Weighted vests for weight-loss maintenance?

A new study tested whether weighted vests can help achieve and sustain weight loss
The post https://peterattiamd.com/weighted-vests-for-weight-loss-maintenance/
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https://peterattiamd.com/weighted-vests-for-weight-loss-maintenance/

#360 ‒ How to change your habits: why they form and how to ...

2025-08-11T04:15:00Z

#360 ‒ How to change your habits: why they form and how to build or break them | Charles Duhigg, M.B.A

"Humans are habit machines. We literally have evolved a brain that is fantastic at making habits.” —Charles Duhigg
The post https://peterattiamd.com/charlesduhigg/
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https://peterattiamd.com/charlesduhigg/

Does eating a diverse array of flavonoids prevent chronic ...

2025-08-09T11:00:00Z

Does eating a diverse array of flavonoids prevent chronic disease?

A critical look at the latest observational study on plant compounds and longevity
The post https://peterattiamd.com/flavonoids-and-chronic-disease/
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https://peterattiamd.com/flavonoids-and-chronic-disease/

Research Worth Sharing, December 2024 Edition Type 2 diabetes in ...

2024-12-21T12:00:00Z

Research Worth Sharing, December 2024 Edition

Type 2 diabetes in youths, extending organ viability, preventative ovary removal, “dark genome” therapeutics, and vascular impacts on physical decline
The post https://peterattiamd.com/research-worth-sharing-december-2024/
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https://peterattiamd.com/research-worth-sharing-december-2024/

Evaluating NAD and NAD precursors for health and longevity NAD ...

2024-12-11T22:00:00Z

Evaluating NAD and NAD precursors for health and longevity

NAD and its precursors – mainly NR and NMN – have garnered attention for numerous purported benefits, but which are supported by evidence?
The post https://peterattiamd.com/nad-for-health-and-longevity/
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https://peterattiamd.com/nad-for-health-and-longevity/