The incredible Spritely Hoot team (Scheme in the browser! WASM tooling!) just released Hoot v0.4.1: https://spritely.institute/news/guile-hoot-v041-released.html
Now with less bugs, lots of little dev improvements, and oh yeah... you can use (define-module) (well, for #:pure modules)!
Plus BONUS: a game jam template for the upcoming Lisp Game Jam: https://gitlab.com/spritely/guile-hoot-game-jam-template