ScienceNode on Nostr: thalidomide acts by promoting the degradation of an unexpectedly wide range of ...

thalidomide acts by promoting the degradation of an unexpectedly wide range of transcription factors – cell proteins that help switch genes on or off – including one called SALL4
https://www.dana-farber.org/newsroom/news-releases/2018/after-60-years-scientists-uncover-how-thalidomide-produced-birth-defects