Hersenvorser, Brain explorer R. Feynman: I’m an explorer? I get curious about everything, and I want to investigate all kinds of stuff. I have been a psychopharmacologist and professor of Biological Aspects of Psychopathology until my retirement in 2013. Now I study the brain and write short assays, see my website. I am also writing a book (provisional title: Our Brain, the Body of the Mind). I use mastodon to keep up with developments in the field. Please post your publications with #neuroscience. I endorse Tootfinder which is an Opt-in global Mastodon full text search.
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Published at
2023-07-19T19:41:49+02:00 Event JSON
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Last Notes npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1qag…9gyn Pattern recognition: ok. But what is the connection with logic? What are"logical patterns?" npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman "We now understand that the human mind is fundamentally not a logic engine but an analogy engine, a learning engine, a guessing engine, an esthetics-driven engine, a self-correcting engine." Hofstadter, Foreword to the New Edition ( of Gödel, Escher, Bach: an Eternal Golden Braid), 2020. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1qzc…yetl If the question is not too private: why did you return to the US? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1ary…md4c Which part of his text do you trust and which do you think is made up? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1hq3…ugxy @npub1gez…kvl3 But how do they come together? Not by thinking seperately about them. Dualism...? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1hq3…ugxy @npub1gez…kvl3 So we can simple ignore these psychologists or their arguments. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1hq3…ugxy @npub1gez…kvl3 Do these psychologists study the brain and psychology? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub19d9…f02p Well, it took me a couple of years reading to understand that. I do not imply that it would take you equally long, but I can not explain it in short. Read Solms M (2021): The hidden spring; a journey to the source of consciousness ISBN 978-1-78283-571-4. To start: why may be not the right question about consciousness being grounded in feelings.You first have to be convinced it is. #neuroscience npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub19d9…f02p The reason is consciousness is (grounded in) feelings about the body in order to maintain homeostasis. This is not a cortical process. This is about basic consciousness, not (yet) selfconsciousness. Any followers to comment on my explanation (or correct it)? #neuroscience npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub19d9…f02p As I understand it, you are talking about the content of consciousness. Some think there is a basic consciousness "before", or without content. Watch the discussion between Metzinger and Friston, the philosopher and neuroscientist resp.: Phenomenology of Pure Consciousness with Thomas Metzinger and Karl Friston (2023): https://www.youtube.com/watch?v=qlPHGnChhI4 npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1w6d…ytvx @npub1gt5…g9em I am with you npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 Congratiolations, looking forward to it (also an ebook I hope) npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub13ey…kkr5 Perhaps this is of interest to you in relation to the brain and chaos theory: https://www.youtube.com/watch?v=mqzyKs2Qvug Starting around min 36 about Steven Grossbergs work. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 I sense a certain amount of moral laziness in the article and answers to your question. I am concerned about that in the same way as I am concerned about moral laziness in my country, see reactions to the results of the recent elections. Do I see a general trend in some (western?) societies? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub18kf…npv5 @npub10ad…tvms Why would "One of the downsides of the ruling is that a company can exclude users with an activated adblocker from accessing its website." be a downside? Its just a consequence of your refusal. Or are you anxious to miss something from a website that wants to force feed? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 That is an interesting question! Let us hear the answers you get. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub19d9…f02p @npub1s4k…j02h @npub15sw…x855 And in relation to what the brain does in real world situations: https://neuromatch.social/@MolemanPeter/111414718571884846 npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1kmk…mtuy Your post reflects the incoherent ideas of Sopolsky npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1twh…5j6z @npub19d9…f02p What would you be reflecting on, seriously, related to your science. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman Brain Inspired 174: Alicia Juarrero: Context Changes Everything (on her ecent book) https://braininspired.co/podcast/174/ On nodes and links in a dynamical system: the nodes may be condensated links, stabale links. Meaning that processes may be most important. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub1qe8…4vky I think they are social-mental-brain disorders. Of course, this is to illustrate that the question: “Are mental disorders brain disorders?” is a no-brainer (pun intended). In fact your positions are similar (or the same?). For me the question is what approach should be primary for a specific patient: the brain, or psychological or social approach. I think some depressions should be seen as biological and antidepressants should be the treatment. Sometimes no additional treatment is neccessary or helpful. Sometimes the biological approach is of no value, but psychological or social help is. The same holds for other major mental disorders. Research into what approach is most helpful for a specific (kind of) patient should go hand-in-hand with diagnostic research, because the (DSM steered) lumping is not helpful in this respect. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub15sw…x855 @npub1t64…u4j0 @npub1zll…lhfq By the way Juarrero is not the only one discussing top-down causation: Noble D (2017): Dance to the tune of life: biological relativity. Cambridge ; New York, Cambridge University Press. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 You may want to read Juarrero, Alicia. Context Changes Everything. She explains rather convincingly top-down causation in all kinds of systems, including biological, without laws of physics being violated. A deep understanding of complex dynamical systems is the basis. In fact causation is not the central issue, but context independent and context dependent constraint are. The "old school" idea of interventionist causation in fact vanishes! Kendler and Woodward write " Some external event happened to each individual ([...] which resulted in a major internal change in them which in turn impacted the risk or course of their disorder. [...] Common clinical (and indeed ‘human’) intuition suggests that these changes were causal." But they do not show or prove that this is not by way of changes at the bottom level. (which I do not belief by the way, see our previous discussion of Kendel's 2005 book). @npub15sw…x855 @npub1t64…u4j0 @npub1zll…lhfq #neuroscience npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub15sw…x855 @npub1t64…u4j0 @npub1zll…lhfq I will read Kendler and Woodward. Perhaps I am able to come up with some sort of an answer. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 @npub15sw…x855 @npub1t64…u4j0 @npub1zll…lhfq You know, of course: This book will argue that because interactional types generated by constraints are multiply realizable, a novel form of mereological causation emerges: top-down causation as distributed control coded in analog form. Juarrero, Alicia. Context Changes Everything (p. 22). MIT Press. Kindle Edition. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman What does not sound as reductionistic is that social and developmental factors can exert actions on the brain. This sounds as two way causality. But then comes in the primacy of genes and neurons. "These changes ... are responsible for initiating and maintaining abnormalities of behavior that are induced by social contingencies." Especially "initiating" is the problem here. This misses the two way causality that is possible in complex dynamical systems (See Jarrero at the bottom). "[...] so can behavior and social factors exert actions on the brain by feeding back upon it to modify the expression of genes and thus the function of nerve cells." Redutionistic is the idea that these expression of genes and function of nerve cells first occur and then cause abnormalities of behaviour. See https://breininactie.com/nature-and-nurture-congenital-and-acquired/: "For everything that we can learn, for all our functions, it is never nature OR nurture. In the developing brain, the contributions of hereditary and environmental factors can never be seen separately." Juarrero A (2023): Context changes everything: how constraints create coherence. Cambridge, Massachusetts, The MIT Press. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 Yes, but the explanation is different in different cases. The example in the article, the woman cured with sugar, may have been caused by spontaneous recovery, or expectation or..... Whatever it may be, the explanation does not need to be called placebo. That is even misleading. If you reserve the placebo effect to expectation, the woman was not cured by placebo if the cause was spontaneous recovery. What the inconsistency is when ascribing causal power to placebo is all in my blog. So what is called placebo is an unexpected or unintended effect. Our ignorance is hidden under the word placebo. npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 But what is the cause of these huge effects? Placebo? npub10r2sk8n02psdx0nnjawlj7k8ln9nrfzzjcqu8eshms2r3rww7w7qg5ccza Peter Moleman @npub1skv…aky3 Nicole, have you read my blog https://breininactie.com/the-placebo-effect-doesnt-exist/?