samsoete
Dr Sam Soete

Decentralised Health Optimisation

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Last Notes

2026-04-11 07:35:54 GMT

Are you side quest maxxing anon?
https://blossom.primal.net/70e6cf7d66e69ecd00c9d59c18d735294f9165a858b76a76a26a195f61ccffd0.jpg
https://blossom.primal.net/aba334af364618903a42a7f8fa2295bdaf2550f2462ff3bdc31bbbb91b973f0e.mp4

2026-04-08 00:32:04 GMT

Gm
https://blossom.primal.net/6b56f8798288ed09d04fb0f3f0f504e3a307602062b8f42d1f98fbfcf20ec052.jpg

2026-03-27 00:08:35 GMT

The difference between people with SIBO that relapse and those who never relapse is quite simple actually.
The former had a label treated and the latter had their physiological dysfunctions identified & fixed.
One treated their illness, the other aimed at optimizing their health.

2026-03-22 21:56:21 GMT

Gm
https://blossom.primal.net/923405caa66db09271854207a29ec4641befb96e60a3a0461df727494138718e.jpg

2026-03-16 02:56:30 GMT

Magical things happen when you replete all micronutrient and microwavelength deficiencies.
Bottlenecks get resolved, optimal pathways are liberated and the flux of vitality that modernity and its environmental mismatches stole from you starts to flow once again.
https://blossom.primal.net/c00b8560a121ee0aafd4763e39eb1c0bd82cdba388f28c2c29082a9d9614ebc2.png

2026-03-10 00:44:13 GMT

Butyrate is the primary fuel source for colonocytes (not glucose).
If you lose your butyrate producers (faecalibacterium, roseburia) → colonocytes lose their preferred fuel → ↓ mito function → ↓ decreased oxygen utilization → ↑ luminal oxygen → obligate anaerobes die off & facultative anaerobes like e. coli expand = dysbiosis
BUT those were the bacteria making the butyrate in the first place so its actually a vicious cycle once this self-regulating system loses its tensegrity.
So in order to fix the microbiome you gotta fix colonocyte energy production and O2 utilization.

2026-02-23 13:15:05 GMT

How many people with auto-immune thyroid disease have inflamed & hyper-permeable guts?
A lot.
https://blossom.primal.net/1698ec87a8c5e5ff316aab4c7902d71c70d591a7a63abcd4fd4ffceb3475b50c.jpg

2026-02-12 08:07:42 GMT

- reply

2026-01-31 10:24:10 GMT

Too many people go through life without a single thing that excites them throughout the day.
Create a mindset that gets excuted about things. Figure out what excites you. Live a life with more of that in it.

2025-12-08 07:30:18 GMT

One of the most commom presentations I see in clients these days:
"I feel like my whole system has been stuck in a constant state of stress, I can’t get my nervous system to calm down or return to a real sense of safety or rest."

2025-11-29 19:14:48 GMT

The brainstem needs a HUGE amount of energy to function optimally and regulates the processes of the body.
If you are dealing with weird symptoms spanning many organ systems, look into the brainstem and energy production.

2025-11-27 06:32:28 GMT

Centralized medicine is unable to square the idea that malnutrition and obesity can coexist.

2025-11-25 23:59:45 GMT

Complex disease stemming from impaired energy metabolism cannot be identified or effectively managed in the centralized model of organ-system hyperspecialization.
This leads to massive amounts of people being diagnosed and essentially gaslighted with "functional disorder" labels.
This model forces an artificual compartmentaluzation of disease/dysfunction = inability to recognize causal factors spanning multiple organ system (such as impaired mitochondrial function leading to low ox phos and dysautonomia).

2025-11-24 03:43:36 GMT

Pharmaceuticals are one of the most underappreciated group of mitochondrial stressors right now.
A large majority of drugs/medications/vaccines damage mitochondria and impair oxidative metabolism.
Statins, SSRIs, antibiotics, vaccine (adjuvants), diabetes meds are some of the worst.
This iatrogenic harm is still unrecognized for the most part.

2025-11-15 05:37:33 GMT

Restoration of meaning and a sense of responsibility (others relying on you) is crucial to addressing the mental health crisis in men.

2025-11-12 10:42:56 GMT

Healing is a function of the body, all it requires is energy
https://blossom.primal.net/5cecf9e7ed3be7f5ccf6819294b80cbd7f2fbae575a5634abe49509886283fa7.jpg

2025-11-10 05:15:51 GMT

The Nature of Expertise
If you want to learn something deeply, the ideal teacher is someone who both understands the subject matter in depth and has firsthand experience applying it. That combination of knowledge & experience constitutes real expertise.
Formal qualifications may signal exposure to centralized knowledge, but they are not a prerequisite for genuine understanding. A person can develop deep expertise through independent study, experimentation, mentorship, and persistent curiosity. What matters most is the depth of comprehension and the ability to apply knowledge critically, not the possession of a credential.
When combined with discernment, critical thinking, and humility, the modern learner has access to nearly all the tools once monopolized by centralized institutions (books, research archives, open discussions, and the global reach of the internet).
Given enough time, discipline, and feedback, a dedicated individual can cultivate legitimate expertise without ever stepping into a traditional institution.
That said, foundational learning often benefits from structured environments. Institutions, when well-run, provide frameworks that help students grasp fundamentals efficiently, expose them to peer discourse, and offer curated access to expert feedback. They also encourage curious pursuit of unanswered questions - that is the beauty of University (the philosophy, not the institution). This scaffolding can prevent blind spots that self-taught learners sometimes develop when they lack structure or guidance. Or skipping foudational concepts leading to a shakey base.
Therefore, in a decentralized soace, it is crucial to constantly test models of understanding with peers (nodes), and relinguish any resemblance of hubris or arrogance.
However, centralized institutions are not without flaws. Their bureaucratic structure often makes them slow to update models of reality, resistant to paradigm shifts, and vulnerable to perverse incentives - whether financial, political, or reputational.
A certificate, at its core, is evidence that someone has completed a prescribed course of study within that system. It is not necessarily proof of wisdom, creativity, or the capacity to think independently.
If someone dismisses an individual due to a lack of credentials without addressing their ideas or refuting their model, something nefarious is going on. There is no excuse for this.
In truth, most knowledge is not locked behind institutional walls. What they primarily offer is organization and access to mentors.
The development of expertise likely requires a balance of both worlds. Centralized structure and guidance, and Decentralized paradigm shifts and ruthless questioning.
https://blossom.primal.net/274cc35ced126179bff98a1f0a44c0b393406b76eae3fdaae761f84e04a06b17.jpg

2025-11-07 22:28:56 GMT

B1 plays a role in the de novo synthesis of neurotransmitters (from glucose) including acetylcholine and glutamate.
The pyruvate dehydrogenase complex (which requires B1) makes acetyl-CoA which can act as a precursor for acetylcholine.
B1 seems to also be involved in ACh release & signalling.
Acetylcholine esterase inhibitors are currently prescribed for Alzheimer's. Interesting stuff.

2025-11-07 01:50:54 GMT

"steady and unhurried, but always in motion."
"slow is smooth, smooth is fast"

2025-11-01 01:43:00 GMT

You have more autonomy over your life than you think (if only one adopts the responsibility for it)
And as you extend the timeframe from days to months to years - that autonomy increases.
Modernity likes to psyop you into thinking you cant do anythujg about your current circumstances.
You have to uncivilize yourself to come to this realisation.

2025-11-01 01:42:39 GMT

I think you want to spend at least one day a week exposed to natural sunlight throughout the ENTIRE day from sunrise to sunset (does not have to be direct).
Ideally its everyday, but that is not feasible for most.
https://blossom.primal.net/780f9f51c9bf6eb17eca3f1ef855f5ea206b0f233f35e39e148319bcb65640f7.jpg

2025-10-30 10:53:53 GMT

Nature doesn't care about convenience.

2025-10-27 00:21:53 GMT

The irony is that nutrient deficiency is quite common in obese populations.
This is high-calorie malnutrition and it leads to impaired energy production at the mitochondrial level resukting in a cascade of cellular -> tissue -> organ dysfunction.

2025-10-19 10:10:46 GMT

Insulin Resistance = Mitochindrial Dysfunction

2025-10-19 06:33:25 GMT

Another beauty
Gm
https://blossom.primal.net/71a6ed6b390e9e3cb19f08322f1185176b3cb52573b9debe20a3ad3b265d62ff.jpg

2025-10-18 17:00:41 GMT

Optimising Immunity > Avoiding Pathogens
The former develops courage and capability, the later breeds fear and weakness.

2025-10-18 13:19:50 GMT

Centralised Medicine = Ptolemaic world view
Decentralised Health = Copernican world view

2025-10-18 11:14:04 GMT

Don't let people manipulate you with cherry-picked data.
Before the 1960s, most children contracted measles, and in developed countries, complications were rare.
Healthy children typically recovered without issues.
However, measles can be dangerous in malnourished children in developing nations or in populations newly exposed to the virus.
Vitamin A & D status is incredibly important.
Research suggests children who recover from measles between ages 4-7 may have lower rates of heart disease later in life (Kubota Y, Iso H, et al). An interesting association potentially relating to immune maturation.
Infants under one year are at highest risk for severe measles, but maternal antibodies from breastmilk provide passive immunity if the mother had natural measles.
Historically, measles mortality dropped sharply before the vaccine due to better nutrition, living conditions, and medical care. Measles parties and vitamin A (cod liver oil) were common preventive measures.
Severe measles cases in children are often linked to vitamin A deficiency.
High-dose vitamin A supplementation during measles infection significantly reduces complications and mortality.
https://blossom.primal.net/bc04d03e4d352790aee25066fedc06e20580bc811c1ad9ccfad65d0a7a841a89.jpg
https://blossom.primal.net/4f41de2c2d53b00a690d29c794b5acc957e9fcb75ef12c294e32a9abefebf9ef.jpg
https://blossom.primal.net/f5861efdd75538c9940053937751cde6f0f2c01df1dc140571f43a9dffb25beb.jpg
https://blossom.primal.net/55f2c69d500bf85d3a6523c7b468a2d5ba08006824714fd028cac404acc00167.jpg

2025-10-18 10:32:59 GMT

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One of the main mechanisms will be vitamin D providing anti-inflammatory effects and improved gut function and GI barrier integrity = less toxins for the liver to deal with in portal circulation.
Then also the mitochondrial energising effects of the near-infrared light will be beneficial to all tissues.

2025-10-18 07:47:24 GMT

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https://blossom.primal.net/0e5b81f8c6545704d8f9e2117a1e8c428277641a9b2ba186908eb6e7d44b2d4b.jpg

2025-10-18 07:45:54 GMT

The answer is yes.
https://blossom.primal.net/7eb74b9ea4f14d045d7eb9c31d02f5cf975d6fe41fa2049916174a627a428e20.jpg

2025-10-18 06:46:29 GMT

There is an underappreciated link between fatty liver/NAFLD and gut inflammation/dysbiosis/hyperpermeability.
When the intestinal barrier breaks down, bacterial endotoxins enter the portal vein.
It drains directly into the liver, so hepatocytes are first exposed to things like LPS.
LPS triggers inflammation, ROS, and TNF-alpha release which impairs mitochondrial function.
Then there is also the bidirectional link between bileflow and dysbiosis.
Ethanol or acetaldehyde produced by certain microbes will overwhelm liver detox pathways.
Many people also have a high ammonia burden due to high urease activity in certain bacterial strains -> more pressure on the liver.
To the extent that dysbiosis impairs SCFA production, you get further metabolic dysfunction.
https://blossom.primal.net/d68a9465c056ce7d3b080f983a2fe3d0eb6566712ba12ff4c7e5679fbac0ac4a.jpg

2025-10-18 06:35:40 GMT

Gm
https://blossom.primal.net/f98f9319a2186e2072f1c51601a3806bb7277e1b9d728f791162f62997d953fb.jpg

2025-10-17 18:12:41 GMT

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50-100mg per 10kg is a good amount

2025-10-17 10:11:25 GMT

Vitamin D is not part of a singular pathway. It is part of a wider network of photochemical transformations & metabolites of which we know very little.
For now, the wisdom of this complex network is hidden & stored in the interaction between our skin & natural sunlight.
It is not found in a vitamin D supplement.Vitamin D is not part of a singular pathway. It is part of a wider network of photochemical transformations & metabolites of which we know very little.
For now, the wisdom of this complex network is hidden & stored in the interaction between our skin & natural sunlight.
It is not found in a vitamin D supplement. https://blossom.primal.net/9215117df1a01fc678ab7c122751e043278751136f13a6f02761f5500233b821.png

2025-10-17 10:00:18 GMT

Excessive caffeine use will also deplete B1 status.
It reduces B1 absorption & increases B1 wasting at the kidney level.
Combine excessive coffee use at work with alcohol consumption after work for long periods of time and you can get into trouble.
Not to mention the synergistic requirements of B1 and magnesium.

2025-10-17 08:59:04 GMT

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I think its very useful if you use quality forms - MgMalate, MgGlycinate, MgTaurinate. You can also use MgChloride in 1/2L of water if titrated slowly over weeks. Been looking into hemp hearts as well, might experiment with those as they are very high in Mg. Most people are deficient, glyphosate for example depletes Mg in our food. Epsom salt baths are another great way to absorb Mg through the skin.

2025-10-17 08:55:36 GMT

Why is the sky blue?
Because of a phenomenon called Rayleigh scattering.
Sunlight looks white, but it’s actually a mix of many colors/wavelengths.
When sunlight enters the atmosphere, it interacts with gas molecules like nitrogen and oxygen.
Shorter wavelengths of light (the blues & the violets) scatter much more strongly than longer wavelengths (red and yellow).
Our eyes are more sensitive to blue than violet, and much of the violet light is absorbed by the upper atmosphere, so we perceive the scattered light as blue.
At sunrise and sunset, the sunlight travels through more atmosphere (x10), scattering away most of the blue light so only the reds and oranges dominate.
https://blossom.primal.net/079ecd40b2c5c299cfccb37ce1577fe8131e633f27fffdd643c74ddfee74df2b.png

2025-10-17 08:32:39 GMT

Magnesium is fundamental to effective vitamin D synthesis and activation.
If you can't get your vitamin D status up, look into magnesium repletion.
https://blossom.primal.net/c16a0a3f2c56f160ede43985a717c955aaa70639a13c245675746da140015d33.png

2025-10-17 06:23:55 GMT

Gm NOSTR
https://blossom.primal.net/3713789bb1ff0b63e0b3c371096221a7ff7521a88f44fbfda7d711075cde6d75.jpg

2025-10-16 09:24:49 GMT

You don’t get a sunburn through glass because UVB is blocked, but you still get UVA & HEV-driven oxidative damage and collagen breakdown, without the NIR spectrum that normally signals repair and resilience.
The protective warning of UVB-induced erythema is gone.

2025-10-16 09:24:37 GMT

Did you know that farm animals living outdoors don't fatten as easily as those living indoors. 🤔

2025-10-16 09:24:27 GMT

A study done in 1939 showing the effects of UV light on testosterone.
"Exposure of the genital region is more effective than the chest."
https://blossom.primal.net/b7a39b7fad9524dbde5a661ed5159e1d53450dc6efa80c37e9f5111d85df10a9.png
https://blossom.primal.net/16094c946ae2422a8b3ad6ed3763a8c7a45ffd42567a7ffb55bf672c862d306c.png

2025-10-16 07:14:29 GMT

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People underestimate how powerful this is for gut health.

2025-10-15 17:55:02 GMT

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Deventeralized Health = Decentralized Wealth

2025-10-15 15:48:00 GMT

Beach reading
https://blossom.primal.net/c10d70f2868fad25fe50aba7a17ba88ce98fd18b769c6b4a48292664ad366f22.jpg
https://blossom.primal.net/ee4d92284a9bd367e756c6bd140cddefb558402087f86608db8c722978b5ae19.jpg
https://blossom.primal.net/68e369aec0d1fe533bc8a86a037edec3ad70d39e6d840799a9a459117192e11c.jpg

2025-10-15 14:11:20 GMT

Does your cardiologist talk about light? https://blossom.primal.net/5c3d3d2d815f0efc12792cdc913ee02019a24299319ff0710be0020ee2ecc0db.png

2025-10-15 14:10:51 GMT

The failing health of humans on this planet is not due to a lack of healthcare spending. If that isn't obvious then I don't know what to tell you.

2025-10-15 12:33:55 GMT

Until centralized medicine fully comprehends the vitamin D INDEPENDENT effects of UV light on regulating human physiology, it will continue to recommend avoiding the sun and replacing it with a vitamin D3 pill.

2025-10-15 11:50:43 GMT

Certain local impairments of enzyme function due to localised heavy metal burden for example can create functional nutrient deficiencies in those organs.

2025-10-14 19:25:58 GMT

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The continual exposure to mismatchedd modern environments is limiting your natural testosterone production and undermining your macsulinity. Male health is faltering and many men are living lives of quiet desperation, wondering why their lust for life has disappeared.
Testosterone levels in men have been declining for decades now. Up to 40% of all tested men are dealing with suboptimal levels of testosterone. That is not normal.
Testosterone and its metabolites not only influences the body's physiology but also shapes a man's mindset and outlook on life. Life fulfillmment is intrinsically tied to proper androgen function. They are bidirectional in nature - as are many things in biology.
There are several reasons why hypogonadism is underdiagnosed.
1. Men hesitate to disclose symptoms of a sexual nature to their doctors due to embarrassment. Moreover, societal conditioning leads them to accept these symptoms as a normal part of aging, dismissing them as unresolvable.
2. Men frequently exhibit vague symptoms like a lack of motivation, depression, and listlessness. Unfortunately, low testosterone is seldom considered as a potential underlying cause for these symptoms.
3. Physicians lack proper awareness regarding hypogonadism and testing is not normalised.
#nevent1q…6vps

2025-10-14 19:06:45 GMT

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Beautiful stuff, love it

2025-10-14 17:50:30 GMT

Are you bench maxxing anon?
https://blossom.primal.net/6858ac008119bbe3cbf85a4c934b7471ecfb0792593c7ecbd91924fce20dd750.jpg
https://blossom.primal.net/98c881982448bf21e188085839507d85de46e543c119080dd26405b2344dbda1.jpg

2025-10-14 13:08:48 GMT

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100%. Couldn't agree more. A lot of unlearning needed to take place, but thats part of the game.

2025-10-14 12:00:11 GMT

If you are dealing with ANY autoimmune condition, you need to expose yourself to more natural sunlight, especially UV light.

2025-10-14 11:55:50 GMT

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Your skin is broadcasting systemic instructions to the rest of the body coded by the light it is exposed to.
#nevent1q…3j0n

2025-10-14 11:55:27 GMT

Here is todays lesson on how Light interacts with your biology.
Mammals only come into contact with UV light through the skin & the eyes.
But its effects are not limited to these peripheral organs that are directly exposed.
UV light, once absorbed, is transduced into chemical, hormonal, and neural signals in a wavelength-specific way, allowing its influence to touch every cell in the body.
https://blossom.primal.net/0491e0aff1d8a1de7675cdd2d9da6d81224d2344fa170054316c2bdd069a540d.png

2025-10-14 11:48:58 GMT

Blessed day.
https://blossom.primal.net/53a4f4e99805447d5532250a9ab6f088ad8abab1230c65b5373781faefaf88d5.jpg

2025-10-14 11:48:49 GMT

Something I am grateful to my medical training for is spending an extensive amount of time studying physiology, metabolism & anatomy.
These foundations have been crucial to build on through my own self-guided learning & exploration.

2025-10-14 06:31:53 GMT

Gm
Never miss a sunrise
https://blossom.primal.net/3ec437bf19a102f2ed755752e024577462ca2b697a9daa415cf84b83879c65da.jpg

2025-10-13 20:24:25 GMT

Centralized Medicine = Searching for diagnostic label to initiate generalized pharmaceutical treatment pathway.
Top-down, disease-centred framework.
Decentralized Health Optimisation = Detecting & Correcting individual imbalances.
Bottom-up, systems biology-based framework.

2025-10-13 20:23:03 GMT

Decentralized medicine empowers everybody to take ownership for their own health.
Nobody is coming to save you. You need to make changes to your own life.
Its a beautiful gift, but an even greater responsibility.

2025-10-13 20:22:18 GMT

Mitochondria lie at the heart of chronic, neolithic disease.
Don't ever forget it. Take care of your colony.

2025-10-13 20:21:39 GMT

Decentralized Health & Decentralized Wealth
This Is The Way
https://blossom.primal.net/78f7d2354fce9fbb4371d367246112ff02eb3a3f579335ccc21f53c6c66d224f.png
https://blossom.primal.net/ba5be2b1bedb9a6692773f84b5763aed54c679ca466a3e59bdbc83dd121775da.jpg

2025-10-13 20:21:09 GMT

Reclaiming sovereignty over my life was one of the core reasons (there are many) to leave the conventional medical system and setup a decentralized health optimisation practice.
Sure, sometimes I still work 10-12hr days, but yesterday for example the sun was shining and I spent the morning getting raw milk and eggs at the farm, called an old friend while walking around in the garden, did client work in the early afternoon, then went for a cycle to a nearby calisthenics park + swim in the sea.
I struggled to live a life where others constantly told me what to do and when to do it, dictated what I could and could not say.
I can still work hard and find purpose in my work, but I can also choose to prioritize sunlight and sea swims when the weather commands it.
https://blossom.primal.net/344905755df10e4d04a5559501818fbc7b0d011edeb93fbb9ea756c0e7b59e72.jpg

2025-10-13 20:19:59 GMT

Centralized medicine is focused on blood sugar and insulin levels.
Decentralized health focuses on what your cells are able to do with that fuel! It looks into mitochondrial function and metabolism.
One optimises for markers that are easily measured, then prescribes drugs to shove glucose into cells, but does nothing to help the mitochondria that are already struggling - that is why cells aren't accepting insulin in the first place.
https://blossom.primal.net/8a4af4e930252dbba78f695d97e1c4bb6365f2233ed72a5cc113da6a84da3320.png

2025-10-13 17:10:36 GMT

My testosterone was 1138ng/dl (2024, retesting soon).
*Yes I will actually show you some receipts.
So what do I do?
- Optimize sleep (9pm-5am +1-2hrs in winter)
- Maximised sunlight exposure especially UV
- Kept my circadian rhythms in sync
- Micronutrient dense diet (animal based)
- Exercised consistently
- Built a healthy amount of lean muscle mass
- Avoided xenoestrogens as much as possible
- Daily grounding as much as possible
- Believed in my often contrarian viewpoints despite mainstream ideology
The fundamentals are what matter. Always.
This is the way.
https://blossom.primal.net/7f5d6b450a1ee972ba139be556df88018f36f7bf43e8d5b533131f163185f7f3.jpg

2025-10-13 14:38:17 GMT

Visual anagrams. Coolest thing I've seen today .
https://blossom.primal.net/5fcec5f565e07a403b9cc85cc83aeac7e67739b12a8a1a9d6e763b72a7531c0c.mp4

2025-10-13 13:40:02 GMT

If you don't make beta endorphins from the sun and moving your body, it will seek opioid substances elsewhere.
https://blossom.primal.net/38142e0c82ca8a618fccaa0b354963036c181052c37af4296ee352d4d667719a.jpg

2025-10-13 12:23:20 GMT

Thiamine requires magnesium to be activated to TPP.
https://blossom.primal.net/36eb2fda70945b4e1e55d478aac2d961e9d63c8af745641488ae4c7b64fe5675.png

2025-10-13 12:12:44 GMT

Drivers of Thiamine Deficiency
1. Dietary Choices
- Refined sugar and carbohydrates
- White rice intake (polished rice)
- Processed foods
- Frequent alcohol consumption
2. Poor Absorption
- Chronic gut issues (SIBO, IBD)
- Thiamine inhibitors (coffee, tea, raw fish)
- Medications (metformin/ diuretics for example)
-General digestive impairment
3. Increased Losses
- Kidney disease
- Diabetes
-Diarrhea or chronic loose stools
- Vomiting
4. Increased Demand
- Excessive exercise
- Surgery or infection
- Pregnancy and lactation
- Hyperthyroidism
- High carbohydrate diet
5. Oxidative Stress
- Impaired antioxidant system
- Environmental Toxicities

2025-10-13 09:46:22 GMT

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In Spain!

2025-10-13 06:35:04 GMT

Gm
https://blossom.primal.net/ec8d90d029b00fe7113c0eec3f7b7f0f74dd455be4efe5606ec32df401bae711.jpg

2025-10-12 17:55:12 GMT

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You got that right 🫡

2025-10-12 17:02:18 GMT

On the importance of spontaneous curiosity & exploration.
"I wonder what's over that hill over there..."
"Where does this little path lead to..."
When this feeling arises, follow it. Always follow it.
Its the path to adventure. Where side quests are found. This is what humans are built for. This is our niche.
https://blossom.primal.net/f37af082a4fa953fe1ac417a5b3aaa05922401bbe9ac82622cf89328f5a28377.jpg
https://blossom.primal.net/1de34716ec2cabe8eae08867f2ba7fe83fa0ef26aedd52330761c8da25347ae4.jpg

2025-10-12 15:23:48 GMT

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Will do

2025-10-12 15:10:02 GMT

My dad always told me I couldn't escape society or its rules. Im doing my best to prove him wrong.

2025-10-12 15:07:50 GMT

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Electric vibes in that picture

2025-10-12 09:54:51 GMT

Life = Structure + Energy + Information

2025-10-12 09:06:03 GMT

The microbiota target mitochondria to regulate their interaction with us.
If this signalling is imbalanced that will result in a mito dysfunction -> cellular dysfunction.
We know that short chain fatty acids have beneficial effects on mitochondrial activity.
Gut health drives healthy mitochondria and the two cannot be separated. This is the holobiont perspective. Systems upon systems. https://blossom.primal.net/3fcb18c86b54cdb516523e7539ab7337db72bbb8fd6adf1839bab9b87415c465.png

2025-10-12 08:32:28 GMT

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100%. Its so much harder to get back

2025-10-12 06:59:24 GMT

Centralized vs Decentralized Medicine:
The allopathic medical system operates on centralized guidelines that are subject to mal-incentives. The game-theory and memetic traits involved in their design lead to them having one primary output: drug prescription.
It does not aim to understand the nature of the body or its ailments. Symptoms are ensnared within the confines of arbitrary diagnostic criteria, channelling the prescription of predetermined drugs.
As a consequence, siloed specialists find themselves confined to a narrow-band of understanding, unable to weave together the intricate tapestry of the individual human being before them.
Decentralized medicine embraces relational and horizontal thinking to generate interconnected comprehension of the human body and its surroundings.
It uses the fundamental laws of nature to gauge its validity which manifest in the efficacy of one's methods.
Practitioners act as individual and exploratory nodes within a decentralized system. Communication between them allows for the gradual but asymptotic movement towards truth, health and vitality.
This is the way.
https://blossom.primal.net/e68747a6b1784df82e30ddb8336d108486ea1ba124e24e8d0a0daa4859e32328.png

2025-10-12 06:39:58 GMT

If you want freedom, you have to take control of your health. It is foundational.

2025-10-12 06:28:02 GMT

Gm
https://blossom.primal.net/e421175bec29589b940340dae4459d3f5350393f46e13501c676a3b2908cb27f.jpg

2025-10-11 20:11:15 GMT

You will be given a vitamin D supplement, which will raise your LDL, then they will give you a statin, which will impair your mitochondria, then you will be given metformin, duloxetine or pregabalin, and on the cycle goes.
Really, all you needed was some sun.
https://blossom.primal.net/ff8992aadf987dba74ffbcfbbbc83127a8a9c09d816121c2b717056c4582c095.jpg

2025-10-11 19:19:18 GMT

We are scared of the wrong things.
We fear alienation.
We fear not fitting in.
We fear criticism, embarrassment and failure.
How about the idea that we have less than 5000 weeks on this earth?
5000 weeks to do something worthy of the gift of life.
This is the way.
https://blossom.primal.net/0f88035263dfb9e2558ede700379bf868d4cfb216a4a648c6c48c246adef669a.jpg

2025-10-11 19:05:04 GMT

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100%

2025-10-11 19:04:03 GMT

What happens to your ability to uncouple your mitochondria and burn of excess calories or regulate temperature when you are on statins and develop a CoQ10 deficiency?
https://blossom.primal.net/79aa2f8ad80c155f55080fd4a74d5417bbfa78d25cf78bd2a96e278a5c7bea6d.png

2025-10-11 19:00:33 GMT

𝗠𝗶𝘁𝗼𝗰𝗵𝗼𝗻𝗱𝗿𝗶𝗮 𝘄𝗶𝗹𝗹 𝘄𝗼𝗿𝗸 𝘀𝘂𝗯-𝗼𝗽𝘁𝗶𝗺𝗮𝗹𝗹𝘆 𝗶𝗳:
1. They receive the wrong fuel (light & food mismatch)
2. Are deficient in key building blocks (CoQ10, B vitamins, Mg, Cu, Zn, Se, fats, etc.)
3. Inhibited by toxins (antibiotics, heavy metals etc.)
4. Levers pulling on mitochondrial function are impaired (thyroid function for example)
https://blossom.primal.net/6fe6b6e95cd59a301983cf8cf73baa44cc357f66dcf8b433ab4b0c40eaa7d957.png
https://blossom.primal.net/cb68f184d1b1b424970650dfb2ef85eafe88ec23ed1d622c6ef6b81a5b88fe82.png

2025-10-11 18:55:56 GMT

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Appreciate you 🙏 will be writing a lot mkre about light and health

2025-10-11 18:54:59 GMT

No words needed.
https://blossom.primal.net/d8ca10bdca4633e9859a6e04d9393b357cbf06b91aeb7dad20757648c2e78b34.jpg

2025-10-11 18:48:54 GMT

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These are beautiful

2025-10-11 18:47:54 GMT

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Hes not lying.
The nervous and endocrine systems are the levers that chronobiology pulls in order to regulate physiology and sync it with the exterior world.
Therefore, in order to rebalance these systems, you have to begin with circadian realignment. Otherwise, all other tools you use will remain ineffective.
#nevent1q…rhcz
https://blossom.primal.net/f6af78fb0764dc2f7b8a0adb26068aad216b2352bd0e595c1e17a963bbb0186f.jpg

2025-10-11 18:36:51 GMT

Butyrate is a mitochondrial nutrient. But its never mentioned alongside CoQ10, PQQ, B vitamins, etc.
1) Direct fuel source
Colonocytes preferentially use it as their main energy substrate. Butyrate enters mitochondria and undergoes β-oxidation → acetyl-CoA → TCA cycle → ATP. Brr.. Very nice.
2) Epigenetic regulation
Butyrate inhibits histone deacetylases or HDACs. Learnt this from mr Greg. This changes gene expression in ways that upregulate mitochondrial biogenesis (via PGC-1α, NRF1/2) and antioxidant defenses.
3. Redox balance
Butyrate metabolism increases NADH and FADH2 supply to the ETC.
4. Anti-inflammatory signaling
Really interested in this one regards to CDR. By dampening NF-KB and upregulating Nrf2 pathways, it reduces chronic inflammation and returns mitochondrial prioritisation to energy production.
5. Mitochondrial quality control
Butyrate might also promote mitophagy and fusion/fission dynamics so that lowers heteroplasmy.

2025-10-11 18:32:06 GMT

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Yes look into Gerald Pollack's and Mae Wan Ho's work. Its called exclusion-zone water. Fascinating stuff.

2025-10-11 18:28:25 GMT

Things that are basically NEVER mentioned in medical school:
- Anything regarding light
- Circadian biology
- Importance of mitochondria
- Biophysics of water
- Toxins (xenoestrogens, glyphosate, heavy metals)
- Importance of micronutrients

2025-10-11 18:27:12 GMT

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I like to base supplement protocols off of data. That is why I test before recommending things because everyone will have different bottlenecks in their metabolism.
Some key nutrients are magnesium, copper, B1, B2, B3, B5, ALA, CoQ10 etc...
Metabolomix+ testing allows me to see where the functional deficiencies are. Also highlights heavy metals toxicities that can impair the enzymes shown above.

2025-10-11 18:24:30 GMT

Sun =
↓ Heart Disease
↓ Stroke
↓ High Blood Pressure
↓ Type 2 Diabetes
↓ Obesity
↓ Fatty Liver Disease
↓ Cancer
↓ Dementia
↓ Autoimmune Disease
↓ Multiple Sclerosis
↓ Type 1 Diabetes
↓ Rheumatoid Arthritis
↓ Infections
↓ Depression
↓ Anxiety
↓ Addiction
↓ Chronic Pain
↓ Bone Fractures
↓ Osteoarthritis
↓ Hormone Dysregulation
↓ Insomnia
↓ Sleep Apnea
↓ Eczema
↓ Psoriasis
But maybe, if you are an idiot, you will have more wrinkles when you are 60?
https://blossom.primal.net/6114e97435bd6c91fc126f1d1ab29c7f5d58cfcfbeff57edb632a25c3a563b6e.jpg

2025-10-11 18:22:22 GMT

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Indeed, its hard to avoid completely these days. Almost all spil is contaminated as well. But reducing exposure as much as possible is key.

2025-10-11 18:21:40 GMT

Could disconnecting from the Earth's electrical field play a role in chronic disease prevalence? 🤔
Shoe sales vs Diabetes growth
https://blossom.primal.net/630815782bc420ce6eb57b81bdcccd08b5aeb54eb36026d50cbace8afc7dc19f.png